![]() 8 Overall, about a third of patients with operable disease have nodal spread. 7 The inguinal lymph node status has been identified as the single most important factor in predicting mortality attributable to vulval cancer. ![]() The standard treatment for squamous cell carcinoma of the vulva is radical surgery, which in all but stage Ia or superficially invasive disease includes inguinofemoral lymphadenectomy. Vulval cancer is curable when diagnosed at an early stage. 2 This trend has been observed in many countries, and has been linked to the rising incidence of vulval intraepithelial neoplasia (VIN) in young women caused by infection with HPV. The proportion of women diagnosed with this cancer under the age of 50 rose from 6% in 1975 to 15% in 2006. 4 Although its peak incidence is in the 7th decade, there has been a significant increase in rates of vulval cancer in younger women. 2 Squamous cell carcinomas (SCC) account for more than 90% of vulval cancers 3 the other 10% include melanomas, sarcomas, basal cell carcinomas and adenocarcinomas. ![]() 2 Mortality data from 2007 shows 384 deaths in the UK. 1 In the UK, it affects approximately 1,063 women every year with a 1 in 316 lifetime risk of developing vulval cancer. Vulval cancer accounts for approximately 3–5% of all gynaecological malignancies and 1% of all cancers in women, with an incidence rate of 1–2/100,000. ![]()
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